Memantin HCl
Product Name : Memantin HCl
Grade : IP / BP / USP
Therapeutic Category : Central Nervous System Agent
CAS No : 41100-52-1
COA : Available
MSDS : Available
Description
- 1 .Memantine Hydrochloride/Memantine HCL
- 2. Cas No:41100-52-1
- 3. MF:C12H21N.HCl
- Use:Alzheimer’s disease treatment
- 5. Appearance:White powder
A xanthine derivative, acebrophylline is used as a bronchodilator for the treatment of bronchial asthma and chronic obstructive pulmonary disease in adults.A dysfunction of glutamatergic neurotransmission, manifested as neuronal excitotoxicity, is hypothesized to be involved in the etiology of Alzheimer’s disease. Targeting the glutamatergic system, specifically NMDA receptors, offers a novel approach to treatment in view of the limited efficacy of existing drugs targeting the cholinergic system.
Memantine is a low-affinity voltage-dependent uncompetitive antagonist at glutamatergic NMDA receptors. By binding to the NMDA receptor with a higher affinity than Mg2+ ions, memantine is able to inhibit the prolonged influx of Ca2+ ions which forms the basis of neuronal excitotoxicity. The low affinity and rapid off-rate kinetics of memantine at the level of the NMDA receptor-channel, however, preserves the physiological function of the receptor as it can still be activated by the relatively high concentrations of glutamate released following depolarization of the presynaptic neuron.
Packaging details
Packaging details: 25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum.
Storage: Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat.
Shelf Life: 5 years if sealed and store away from direct sun light.
Additional Information
The most widely recognized markets for this item incorporate the accompanying nations. If you don’t mind ask with us if your nation or district isn’t recorded:
ASIA: Saudi Arabia, Singapore, Syria, Philippines, Turkey, Turkmenistan, Afghanistan, Israel, Jordan, Pakistan, Russia, Uzbekistan, Yemen, Vietnam, Indonesia, Malaysia, Iran, Tajikistan, and so forth..
AFRICA: South Africa, Uganda, Ethiopia, Libya, Sudan, Congo, Gambia, Ivory Coast, Nigeria, Ghana, Kenya, Mauritius, Botswana, Egypt, and so forth.
NORTH & SOUTH AMERICA: Dominican Republic, Argentina, Guatemala, Guyana, Peru, Bolivia, Venezuela, USA, Canada, Panama, Trinidad and Tobago, Costa Rica, Puerto Rico, Brazil, Bahamas, Ecuador, and so forth .
EUROPE: France, Georgia, Germany, Hungary, Ireland, Iceland, Netherlands, Norway, Austria, Azerbaijan, Belarus, Belgium, Cyprus, Czech Republic, Denmark, Poland, Spain, Sweden, Switzerland, Ukraine, United Kingdom (UK) , Latvia, and so forth.
OCEANIA: Fiji, Australia, New Zealand, and so forth.
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