Travoprost – Chemconpharma

Description

Travoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure. It is a synthetic prostaglandin analog (or more specifically, an analog of prostaglandin F2α) that works by increasing the outflow of aqueous fluid from the eyes.

Specification

Appearance Clear colorless to light yellow oily liquid (Result: Confirm)
Solubility Very souble in acetonitrile and ethanol, practically insoluble in water (Result: Confirm)
Identification
- TLC: appear as black spots (Result: Confirm)
- HPLC: the retention time of the major peak in the chromatogram of assay preparation corresponds to that of the standard preparation as obtained in the Assay (Result: Confirm)
Optical rotation +52.0°~+58.0° (anhydrous and solvent free basis) (Result: +53.6°)
Water NMT 1.0% (Result: 0.1%)
Residual solvents Ethyl acetate: NMT 0.5% (Result: ND)
Related substances
- USP travoprost related compound A RS: NMT 0.2% (Result: ND)
- Epoxide derivative : NMT 0.4% (Result: 0.01%)
- 15-epi Diastereomer: NMT 0.1% (Result: 0.01%)
- 5,6-trans Isomer: NMT 3.5% (Result: ND)
- 15-Keto derivative: NMT 0.3% (Result: 0.01%)
- Any other individual impurity: NMT 0.1% (Result: ND)
- Total impurities: NMT 4.0% (Result: 0.02%)
Assay 96.0%~102.0% (anhydrous and solvent free basis) (Result: 98.9%)
Conclusion Conform to Enterprise standard.

Packaging details

Packaging details: 25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum.

Storage: Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat.

Shelf Life: 5 years if sealed and store away from direct sun light.

Additional Information

The most widely recognized markets for this item incorporate the accompanying nations. If you don’t mind ask with us if your nation or district isn’t recorded:

ASIA: Saudi Arabia, Singapore, Syria, Philippines, Turkey, Turkmenistan, Afghanistan, Israel, Jordan, Pakistan, Russia, Uzbekistan, Yemen, Vietnam, Indonesia, Malaysia, Iran, Tajikistan, and so forth..

AFRICA: South Africa, Uganda, Ethiopia, Libya, Sudan, Congo, Gambia, Ivory Coast, Nigeria, Ghana, Kenya, Mauritius, Botswana, Egypt, and so forth.

NORTH & SOUTH AMERICA: Dominican Republic, Argentina, Guatemala, Guyana, Peru, Bolivia, Venezuela, USA, Canada, Panama, Trinidad and Tobago, Costa Rica, Puerto Rico, Brazil, Bahamas, Ecuador, and so forth .

EUROPE: France, Georgia, Germany, Hungary, Ireland, Iceland, Netherlands, Norway, Austria, Azerbaijan, Belarus, Belgium, Cyprus, Czech Republic, Denmark, Poland, Spain, Sweden, Switzerland, Ukraine, United Kingdom (UK) , Latvia, and so forth.

OCEANIA: Fiji, Australia, New Zealand, and so forth.